msem-instigator

Target player sacrifices a creature.
Create a Vial token. (It's an artifact with “{1}, Sacrifice this and another permanent: Draw a card. Activate only during your turn.”)

Whenever one or more creatures die for the first time each turn, you draw a card and you lose 1 life.
Whenever you cast a black noncreature spell, Villainy deals 2 damage to any target and you gain 2 life.

{G}{W}, {T}: Remove a -1/-1 counter from target creature.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Draw two cards, then discard two cards.
Agonize (You may cast this card from your graveyard by putting a -1/-1 counter on a creature you control in addition to paying its other costs. Then exile this card.)

Vigilance
Whenever you make first contact, put a +1/+1 counter on Volarian Sightseer. (You make first contact the first time each turn you cast a spell with a name not in your graveyard or control already.)

Reveal cards from the top of your library until three creature and/or land cards are revealed this way. Put all creature and/or land cards revealed this way into your hand and the rest into your graveyard.

Ward {2} (Whenever this creature becomes the target of a spell or ability an opponent controls, counter it unless that player pays {2}.)
Whenever you cast a spell during an opponent's turn, tap target nonland permanent.

Defender
When Wall of Ivy enters, create a Vial token. (It's an artifact with “{1}, Sacrifice this and another permanent: Draw a card. Activate only during your turn.”)

Defender
When Wall of Rime enters, tap target creature an opponent controls. That creature doesn't untap during its controller's next untap step.

Defender
Whenever Wall of Seclusion blocks a creature, that creature doesn't untap during its controller's next untap step.

Whenever Wandering Conqueror attacks, it explores. (Reveal the top card of your library. Put it into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then you may put that card in your graveyard.)
As Wandering Conqueror explores a land, you may put that card into your graveyard. Whenever you do, Wandering Conqueror deals 2 damage to target player or planeswalker.

Flash
Whenever a permanent with an Adventure you control enters, put a +1/+1 counter on Wandering Dingo.

Lifelink, haste
Wanton Cleaver has first strike as long as it's attacking.

Each instant and sorcery card in your graveyard gains agonize until end of turn.
Agonize (You may cast this card from your graveyard by putting a -1/-1 counter on a creature you control in addition to paying its other costs. Then exile this card.)

First strike
Wither (This deals damage to creatures in the form of -1/-1 counters.)

Advance {3} (Cast this for {3} to advance it as it enters. {3}: Advance this as a sorcery.)
Whenever Wastes Scrambler advances, put your choice of a +1/+1, first strike, menace, trample, or vigilance counter on it. If {R}{W}{B} was spent to advance it, repeat this process twice.
Crew 1

Vigilance, reach
Watchful Authority can block an additional creature each combat.

Whenever Wavering Sorcerer attacks, you may switch its power and toughness until end of turn.
Unveil {3}{U}{R} ({3}{U}{R}: Transform this. Unveil only as a sorcery.)

Advance {5}{B}{B} (Cast this for {5}{B}{B} to advance it as it enters. {5}{B}{B}: Advance this as a sorcery.)
Whenever Well-Oiled Sniper advances, target creature gets -3/-3 until end of turn.

Wharf Lumper can't be blocked by creatures with greater power.
Whenever Wharf Lumper attacks, mill a card. If that card was an instant or sorcery, Wharf Lumper gets +3/+0 until end of turn.

When Wild Waypoint enters, create a 1/1 green Scout creature token.
{T}: Add {B}, {G}, or {U}.

When Witch's Invitation enters, you may put a -1/-1 counter on target creature.
{2}, {T}: Tap target creature with a -1/-1 counter on it.

Whenever you cast a spell, you may pay {1}. If you do, Wizened Tortle explores. (Reveal the top card of your library. Put it into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then you may put that card in your graveyard.)

Vigilance
Whenever a creature you control survives damage, it explores. (Reveal the top card of your library. Put it into your hand if it's a land. Otherwise, put a +1/+1 counter on this creature, then you may put that card in your graveyard.)

[+2]: Put a -1/-1 counter on or remove a -1/-1 counter from up to one target creature.
[–1]: Draw a card, then each player sacrifices a nonland permanent.
[–10]: Destroy all nonland permanents you don't control.