msem-instigator

[+1]: Each opponent puts a -1/-1 counter on a creature they control.
[–1]: Exile target card in a graveyard. You gain life equal to its mana value.
[–6]: Choose a number. You draw that many cards and you lose that much life.

{3}{B}, {T}: Choose a card name. Target player reveals cards from the top of their library until they reveal a card with the chosen name. If they do, put the revealed cards into their graveyard. Otherwise, they shuffle their library.

Inquisitor's Chamber enters tapped.
{T}: Add {B}.
{B}{B}, {T}, Sacrifice another permanent: Draw a card.

Whenever Insatiable Abomination or another Horror you control enters, each player mills four cards.
Exile a creature card from your graveyard: Tap target Horror you control. It gains indestructible until end of turn.

You may have Insipid Metamorph enter as a copy of any other creature on the battlefield, except it's 1/1.

Escalate {R} (Pay this cost for each mode chosen beyond the first.)
Choose one or both —
• Untap all creatures you control.
• Take an extra turn after this one. Skip the untap step of that turn. Exile Inspire Actuality.

{2}, {T}: Put a +1/+1 counter on target creature you control.
{2}, {T}, Sacrifice Inspiring Effigy: Put a +1/+1 counter on each creature you control.

Whenever you cast or copy an instant or sorcery spell this turn, Instant of Brilliance deals 1 damage to each opponent.
Copy target instant or sorcery spell you control. You may choose new targets for the copy.

Exile the top card of your library. Until end of turn, you may play that card. If that card is an instant or sorcery card, it costs {2} less to cast this turn.

Prowess (Whenever you cast a noncreature spell, this creature gets +1/+1 until end of turn.)
{U}{R}: Target creature without prowess gains prowess until end of turn. Activate only if Intelligence is in your graveyard.

Whenever a +1/+1 counter is put on a creature you control, scry 1.
Each creature you control with a +1/+1 counter on it has lifelink.

Whenever a creature enters, it deals damage equal to its power to any target of its controller's choice.
When Interplanar Raid enters, you may aetherize target creature you control. (To aetherize, create a token that's a copy of it, then exile that token.)

Flying, ward {2}
Intisuyu's Masterpiece gets +X/+X, where X is the number of artifacts and/or enchantments you control.

Whenever you tap a land for mana, add one mana of any type that land produced.
Sacrifice Into Strange Territories: Untap up to two lands.

When Into the Unknown enters, create two 1/1 Scout creature tokens that are all colors.
Whenever a land you control enters, if it doesn't have the same name as another land you control, put a +1/+1 counter on each creature you control.

Flying
When Intrepid enters, search your library for a land card, reveal it, put it into your hand, then shuffle.
Wanderlust — {0}: Intrepid becomes an artifact creature until end of turn. Activate only if you control four or more differently named lands.

At the beginning of combat on your turn, create a 1/1 blue and red Pirate creature token with haste. That token attacks this combat if able.
Whenever Intrepid Captain attacks, other attacking Pirates you control get +1/+0 until end of turn.

({T}: Add {U}.)
Inundated Sanctuary enters tapped with two sanctum counters on it.
{T}, Remove a sanctum counter from Inundated Sanctuary: Add {W} or {B}.

Counter target spell unless its controller pays {1}.

Draw X cards.
Flashback—{U}{U}{U}, Sacrifice X permanents. (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Inversion of Flesh deals 5 damage to each creature and each planeswalker, and 5 damage to each player with the highest life total or tied for highest life total among players.

Hexproof
Invisible Stalker can't be blocked.

Target opponent reveals cards from the top of their library until they reveal two instant and/or sorcery cards. Exile those cards, then that player shuffles the rest into their library. You may cast cards exiled this way until end of turn, and you may cast them without paying their mana costs.

Look at the top eight cards of your library. You may put a creature card from among them onto the battlefield and exile an instant or sorcery card from among them. Put the rest on the bottom of your library in a random order. As long as that creature is on the battlefield, whenever it deals combat damage to a player, copy the exiled card and you may cast the copy without paying its mana cost.

Search your library for a Demon card or a black card with mana value 6 or greater, reveal it, put that card in your hand, then shuffle.