msem-instigator

As an additional cost to cast this spell, discard a card or pay {4}.
Destroy target creature.

Destroy target creature. If an opponent lost life this turn, that creature's controller mills five cards.

Destroy target creature or planeswalker. If you controlled a black legendary creature or planeswalker as you cast this spell, that permanent's controller loses X life and you gain X life, where X is that permanent's mana value.

When Shadow of Izumito dies, choose one —
• Destroy target creature that was dealt damage this turn.
• You may put a progress counter on a Project you control.

When Shark Slayer enters the battlefield, you may destroy target creature with mana value less than or equal to the number of artifacts you control.

Destroy target creature if it has mana value 4 or greater. If Shatter Facade was cast from exile, destroy that creature if it has mana value 3 or less instead.
Orchestrate {B} (You may exile this card from your hand anytime you could cast a sorcery for its orchestrate cost. When you next resolve a spell, you may cast this from exile without paying its mana cost.)

Destroy target creature. It can't be regenerated.

Destroy target creature with power 4 or greater.

Destroy target creature with flying. (Then exile this card. You may cast the creature later from exile.)

Destroy target creature unless its controller pays {3}.

Destroy target creature. Then if you control a Wizard, that creature's controller loses 1 life for each creature card in their graveyard.

Menace
When Spaceship Invader enters the battlefield, destroy target creature you don't control with mana value 3 or less.

If an ability of a creature or planeswalker an opponent controls was activated this turn, you may pay {1}{B} rather than pay Spike Wall Trap's mana cost.
Destroy target creature or planeswalker.

Choose one —
• Destroy target creature with flying.
• Destroy target artifact.

As an additional cost to cast this spell, sacrifice a creature.
Destroy target creature.

As an additional cost to cast this spell, torment yourself. (You lose 3 life unless you discard a card or sacrifice a nonland permanent.)
Destroy target creature.

[+2]: Up to one target creature gets -1/-1 until your next turn. Tap it. You may remove all counters from it.
[–2]: Destroy target creature with no counters on it.
[–10]: Each opponent's life total becomes equal to the number of creatures they control.

Destroy target creature with mana value X or less.

Destroy target creature. Then if there are ten or more cards in your graveyard, return target creature card from your graveyard to your hand.

Until end of turn, target creature you control gains “{T}: Destroy target creature.”

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
Destroy target creature you don't control with the greatest power.
I — Until your next turn, prevent all damage that would be dealt to you and planeswalkers you control.
II — Exile target card from a graveyard. You gain 2 life.

At the beginning of your upkeep, destroy target creature with the greatest power or tied for greatest power among creatures on the battlefield. Then if there are no creatures on the battlefield, sacrifice The Empty Throne.

Return target creature card from your graveyard to the battlefield, then destroy target creature an opponent controls that doesn't share a creature type with it.

Destroy target creature with power less than or equal to the number of creature cards in your graveyard.

Destroy target creature with no counters on it and no permanents attached to it.